IGF-2: Potential Drug Target for Various Diseases (P21697)

Target Name: Insulin-like growth factor 2 mRNA-binding protein 1 (isoform 2)

NCBI ID: P21697

Insulin-like growth factor 2 mRNA-binding protein 1 (isoform 2)

IGF-2: Potential Drug Target for Various Diseases

Insulin-like growth factor 2 (IGF-2) is a transmembrane protein that plays a critical role in the growth and development of many organisms, including humans. IGF-2 is a member of the insulin-like growth factor family, which includes a variety of proteins that are involved in the regulation of growth and development. One of the IGF-2 proteins that has garnered particular interest is ISOform 2, a 21-kDa protein that is highly expressed in various tissues and organs.

ISOform 2 is a member of the VICKZ family, which includes a variety of non-coding RNAs that are involved in the regulation of gene expression. These non-coding RNAs are called microRNAs (miRNAs) and are derived from double-stranded RNA viruses. The VICKZ family has been identified as a potential drug target in the context of various diseases, including cancer, neurodegenerative diseases, and developmental disorders.

One of the unique features of ISOform 2 is its ability to interact with miRNAs. This interaction between ISOform 2 and miRNAs allows for the regulation of gene expression and can potentially serve as a drug target. The regulation of gene expression by ISOform 2 and miRNAs is critical for the development and maintenance of various tissues and organs, including the brain, heart, and blood vessels.

ISOform 2 has also been shown to play a role in the regulation of neural development and plasticity. It has been shown to promote the survival of neurons and to regulate the formation of new neurons in the brain. in the regulation of synaptic plasticity, which is the ability of the brain to change and adapt over time.

In addition to its role in neural development and plasticity, ISOform 2 has also been shown to play a critical role in the regulation of wound healing and tissue regeneration. It has been shown to promote the growth and proliferation of cells in response to an injury or wound, which is important for the development of new tissues and organs.

ISOform 2 has also been shown to play a role in the regulation of immune responses and inflammation. It has been shown to promote the production of immune cells in response to an infection or inflammation, which is important for the defense against external threats.

In conclusion, ISOform 2 is a protein that has the potential to serve as a drug target or biomarker for a variety of diseases. Its ability to interact with miRNAs and its role in the regulation of neural development, plasticity, wound healing, and immune responses make it an attractive target for manipulation for the treatment of various diseases. Further research is needed to fully understand the role of ISOform 2 in these processes and to determine its potential as a drug or biomarker.

Protein Name: Insulin-like Growth Factor 2 MRNA-binding Protein 1 (isoform 2)

The "Insulin-like growth factor 2 mRNA-binding protein 1 (isoform 2) Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about Insulin-like growth factor 2 mRNA-binding protein 1 (isoform 2) comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
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